Do the adaptive mechanisms described above compensate for the decrease in oxygen available at altitude. The answer is NO. Even with acclimatization, the proportion of the energy supplied by anaerobic metabolism for any level of activity (rather than by oxygen supported or aerobic pathways) increases and performance suffers.
Does hypoxic exercise at altitude provide a training benefit? This is controversial, but controlled studies in trained athletes have not been confirmed any benefit for hypoxic exercise WITHOUT CONCOMITANT ACCLIMATIZATION.
And the direct effects of interval training to stress and improve an athlete’s maximum aerobic capacity (VO2 max.) definitely deteriorate with training at elevation as a result of the inability to maintain a VO2 max. comparable to sea level when training in a hypoxic environment. During interval work outs, speed, oxygen uptake, heart rate, and lactate levels are all lower than those from lower altitudes suggesting that interval training is best performed as near sea level as possible.