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03 19th, 2010| 
Book Description:
In consolidation of the most updated experimental results and perspectives from diverse research fields on a main theme - Intermittent Hypoxia, this book encompasses the structural, physiological, pathophysiological, biochemical, genetic, metabolic, and therapeutic aspects of intermittent hypoxia and provides an open forum to promote the bench-to-bed translational implications of both adaptive (beneficial) and maladaptive (detrimental) responses to intermittent hypoxia in animals and humans. Authored by 74 leading scientists from 17 countries in Asia, Europe, North America, and Oceana, the 30 chapters are grouped under 7 different sections covering the profound effects of intermittent hypoxia particularly on cardiovascular, respiratory, nervous, and skeletal muscular systems. Special attentions are paid to the protective or injurious roles played by intermittent hypoxia and their underlying cellular and molecular mechanisms in several major human diseases such as acute myocardial infarction, stroke, sleep apnea, and Parkinson’s disease. Several chapters have also reviewed the use of intermittent hypoxia training for enhancing exercise performance in elite athletes. Overall, as endorsed by Professor John B. West (Member, Institute of Medicine, National Academy of Sciences of U.S.A.; Editor-in-Chief, High Altitude Medicine and Biology) through his Foreword for the book, this is the most comprehensive monograph to date on the topic of intermittent hypoxia, which can cause significant structural and functional impact on the systemic, organic, cellular and molecular processes of human physiology and pathophysiology. Hence, this book could serve as a thorough reference for research scientists, physicians, academic faculty, graduate and medical students, athletic coaches and trainers, who are interested in enhancing their knowledge about the past, present, and future of intermittent hypoxia research and its translational applications for prevention and treatment of major diseases and improving exercise performance.
Centinaio, A., Cominardi, M., Bergero, D., Rose, G. A., McLeod, G.
L.P. Veterinario FEI, Clinica Veterinaria della Brughiera, Via Monte Rosso 51, Cardano al Campo (VA), Italy.
The aim of this preliminary work was to evaluate the effects of a new machine (GO2Altitude) in horses with haemolytic parasite infections or anaemia compared to traditional drug therapy. The study was carried out on two groups of horses. Group I included 44 horses that were positive for haemolytic parasitoses, and was then subdivided into two subgroups depending on the therapy followed: Group I/A, 22 horses treated with a sterilizing therapy and traditional reconstituent therapy and Group I/B, 22 horses treated with a sterilizing therapy and afterwards with the GO2Altitude. Group II included horses that, although did not have important alterations in their blood parameters, had underlined a number of red blood cells near the lowest physiological limit (threshold for anaemia). Two subgroups were obtained following the treatment used: Group II/A, 10 horses treated with traditional reconstituent therapy and Group II/B, 10 horses treated with traditional reconstituent therapy (10 days treatment) and afterwards with GO2Altitude. A first blood sample was taken before any kind of treatment; a second sample was taken after 20 days and a third at 50 days from the first blood sample. Erythrocytes, haemoglobin, haematocrit, MCH, MCHC and MCV were evaluated in each sample. For the horse near the threshold for anaemia, the innovative treatment proposed improved these parameters. The results obtained confirm the initial hypothesis of the efficiency of GO2Altitude to help recover those subjects with haemoparasitic pathologies and with anaemia, and therefore places interesting perspectives to a wide range of use of this instrument for the sport horse.